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Qian Liu

Qian Liu

Zhengzhou University People’s Hospital, China

Title: Clinical analysis of pediatric glaucoma in central China

Biography

Biography: Qian Liu

Abstract

Purpose: We aimed to describe the characteristics, epidemiology, management and outcomes of glaucoma in pediatric patients in central China.

Methods: This study retrospectively analyzed inpatients with pediatric glaucoma at Henan Provincial People’s Hospital, Henan Eye Institute and Henan Eye Hospital between 2017 and 2020.

Results: Overall, 239 cases (276 eyes) of pediatric glaucoma in patients, comprising 87 girls (36.40%) and 152 boys (63.60%) were analyzed. The mean age was 6.65 ± 4.46 and 2.93% of the patients had a family history of glaucoma. Primary Congenital Glaucoma (PCG) was the most common type of glaucoma, followed by traumatic glaucoma in 8.33% of the patients, which was considered secondary glaucoma. The most common signs and symptoms were elevated Intra Ocular Pressure (IOP) and eye pain. Trabeculotomy (Trab) and Microcatheter-Assisted 360° Trabeculotomy (MAT) combined with Trab were the most commonly performed surgeries. The IOP of patients with PCG, Juvenile Open-Angle Glaucoma (JOAG) and secondary glaucoma were 15.27 ± 7.48 mmHg, 17.16 ± 10.05 and 18.65 ± 8.55 respectively, at the final follow up. The rate of re-operations in patients with PCG, JOAG and secondary glaucoma were 9.15%, 6.78% and 4.69% respectively. The mean visual acuity of the eyes with PCG, JOAG and secondary glaucoma was 0.79 ± 0.68, 0.51 ± 0.48 and 0.53 ± 0.50 respectively. There were 135 cases (150 eyes) before the epidemic of novel coronavirus and 93 cases (105 eyes) after the epidemic of COVID-19. Primary Congenital Glaucoma (PCG) was the most common type before and after the epidemic of novel coronavirus, accounting for 67.41% and 67.74% respectively, while developmental glaucoma was the most significant difference before and after novel coronavirus's epidemic, 14.07% and 26.88% respectively. The most common signs of novel coronavirus before and after the epidemic were elevated IOP, which were 33.33% and 38.91% respectively. The other 11 cases were treated before and after the epidemic of novel coronavirus, 7 cases were treated with binocular therapy and 4 cases with the same eye.