Corneal Science – Healing & Regeneration

Corneal science is rapidly advancing with breakthroughs in regenerative medicine, tissue engineering, and refractive restoration. Sophisticated diagnostic imaging such as corneal topography, Scheimpflug tomography, and epithelial mapping provides clear insights into biomechanical stability and early ectatic changes. Innovations in keratoconus management, including cross-linking customization and next-generation intracorneal ring technologies, are restoring structural integrity with greater precision. Bioengineered corneal substitutes, decellularized scaffolds, and stem-cell–derived epithelial layers are offering promising alternatives to traditional transplantation, addressing global donor shortages. Femtosecond laser–assisted lamellar keratoplasty continues to improve visual outcomes, while advances in therapeutic contact lenses and biomimetic hydrogels are accelerating epithelial healing. Molecular research is uncovering pathways involved in inflammation, nerve repair, and corneal sensory restoration, supporting improved treatments for infections, dystrophies, and neurotrophic disease. Collectively, these developments are transforming corneal care through personalized diagnostics and regenerative strategies that enhance transparency, function, and long-term ocular surface health.

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