Ophthalmology and Vision Science

Ophthalmic Drug Delivery – Novel Formulations

Ophthalmic drug delivery research is focused on improving therapeutic efficacy, reducing treatment burden, and enhancing patient adherence. Traditional topical formulations face challenges such as rapid tear washout, limited bioavailability, and frequent dosing requirements. Novel delivery systems—including nanoparticles, microneedles, in-situ gels, liposomes, and sustained-release implants—are revolutionizing how medications reach ocular tissues. These technologies enable targeted penetration to the cornea, retina, and posterior segment with fewer systemic effects. Gene-based delivery platforms and biologic formulations are expanding options for chronic diseases such as macular degeneration, glaucoma, and uveitis. Smart contact lenses, drug-eluting materials, and biodegradable carriers offer new pathways for long-term controlled release. Improved pharmacokinetics, precision targeting, and polymer-based innovations support more reliable therapeutic outcomes. These advancements reflect a growing commitment to patient-centered design and improved quality of care across ophthalmology.